Pom1 gradient buffering through intermolecular auto‐phosphorylation
نویسندگان
چکیده
منابع مشابه
Pom1 gradient buffering through intermolecular auto-phosphorylation
Concentration gradients provide spatial information for tissue patterning and cell organization, and their robustness under natural fluctuations is an evolutionary advantage. In rod-shaped Schizosaccharomyces pombe cells, the DYRK-family kinase Pom1 gradients control cell division timing and placement. Upon dephosphorylation by a Tea4-phosphatase complex, Pom1 associates with the plasma membran...
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Concentration gradients regulate many cell biological and developmental processes. In rod-shaped fission yeast cells, polar cortical gradients of the DYRK family kinase Pom1 couple cell length with mitotic commitment by inhibiting a mitotic inducer positioned at midcell. However, how Pom1 gradients are established is unknown. Here, we show that Tea4, which is normally deposited at cell tips by ...
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ژورنال
عنوان ژورنال: Molecular Systems Biology
سال: 2015
ISSN: 1744-4292,1744-4292
DOI: 10.15252/msb.20145996